It affects the nervous system of parasites, leading to their death, but is considered non-toxic to mammals. As with any product, consult your veterinarian before using this product on debilitated, aged, pregnant or nursing animals. Safe for use with pregnant or nursing dogs and cats. WHO Acute Hazard classification of pesticides: Class II, moderately hazardous. Imidacloprid (1-[(6-chloro-3-pyridinyl) methyl]-N-nitro-2-imidazolidinimine) is a chloronicotinyl nitroguanidine insecticidal agent. In cats oral intake due to intense grooming can cause hypersalivation (drooling), vomit, breathlessness. Cats exposed to toxic chemicals may not exhibit all of the signs of poisoning. For this reason disposal of imidacloprid residues (e.g. The half-life of imidacloprid in soil is quite long, 48 to 190 days. Do not contaminate feed or food. The treatment schedule should be based on the local epidemiological situation. ducks). Click here for a list and overview of all safety summaries of antiparasitic active ingredients in this site. Due to the large safety margin of imidacloprid, signs are rarely seen. and cats are products used to control rodents; baits applied for slug and snail control; herbicides applied to lawns; and insecticides used in flea collars and spot-on products. Flumethrin is a fat-soluble pyrethroid insecticide and acaricide used in the control of ectoparasites on farmed livestock like cattle, sheep, goats and horses, and domestic animals such as dogs. Imidacloprid is a chloronicotinyl nitroguanidine insecticide. Treatment of cats with Advantage rapidly kills fleas and may reduce the incidence of this condition. It has moderate acute mammalian toxicity following oral administration, but low toxicity if inhaled or applied to the skin. Imidacloprid Side Effects, Adverse Drug Reactions (ADRs) and Warnings. In case of dermal exposure rinse the skin with abundant water and soft detergents. 1 The manufacturer states that these products should be used with caution in debilitated, aged, pregnant, or nursing animals, and kittens or puppies less than 4 months of age. Ingested imidacloprid is vastly absorbed to blood and quickly metabolized in the liver. Summary of toxicity testing for health effects identified in the Health Standa rds Statute (144.0751): Even if testing for a specific health effect was not conducted for this chemical, information about that effect might be available from studies conducted for other purposes. Imidacloprid is not a reproductive or developmental toxicant and is not … To Physician: Treat the patient symptomatically. There is a certain risk of groundwater contamination in porous soils. Toxicity of inerts to cats: An uniden-tified inert ingredient in Advantage, an imidacloprid flea insecticide applied as drops on the back of a pet’s neck, can be toxic to kittens when applied above the label rate. 9 Citations; 638 Downloads; Abstract. Imidacloprid is an insecticidal agent that acts on the central nervous system of insects causing impairment and subsequent death. 1 Imidacloprid spot on products are labeled to kill adult fleas and their larvae in dogs and cats. Before using or dispensing any product, read and carefully observe the label directions. and Under. Regulations for product use are established by country. Imidacloprid is very toxic to aquatic invertebrates, toxic to upland game birds, and of low toxicity to fish. 3. Imidacloprid is also highly toxic to bees. WHO Acute Hazard classification of pesticides. TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER MAKES NO OTHER EXPRESS OR IMPLIED WARRANTY, INCLUDING ANY OTHER EXPRESS OR IMPLIED WARRANTY OF FITNESS OR MERCHANTABILITY, and no agent of Bayer is authorized to do so except in writing with a specific reference to this warranty. When it comes to insecticide … … 11556-118, Manufactured For Bayer HealthCare LLC, Animal Health Division, Shawnee Mission, Kansas 66201 USA, Bayer, the Bayer Cross and Advantage are registered trademarks of Bayer, Advantage is protected by the following U.S. patents: 6,232,328 and 6,001,858. In addition, it is marketed for the diagnosis and control of varroatosis in bee hives. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Finished products contain one or more active ingredients, but also other ingredients that can be relevant from the safety point of view. Once-A-Month Topical Flea Treatment for Cats and Kittens 8 Weeks and Older. Do not contaminate water, food or feed by storage or disposal. Place in trash or offer for recycling if available. If you intend to use a veterinary drug containing this active ingredient you must carefully read and follow the safety instructions in the product label. It has been used in products sold in the United States since 1994. This page contains information on Advantage 18 (imidacloprid) Topical Solution for Cats and Kittens (8 Weeks and Older, Over 9 lbs.) Advantage Multi® for Cats(10% imidacloprid + 1% moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. Pull cap off tube. Always ask your veterinary doctor, or pharmacist, or contact the manufacturer. (12%) for cats], has also been included with several of the products containing fipronil (e.g. This allows a rather long residual effect against. Imidacloprid has a favorable toxicity profile, due to preferential activity for the nAChR subtype that occurs in insects and poor penetration of the vertebrate blood–brain barrier to reach sensitive nAChR sites in the central nervous system. Do not use on unweaned kittens or puppies. Once a cat has tasted imidacloprid it will never forget the memory of the smell. Hold applicator tube in an upright position. Imidacloprid is used to control sucking insects, termites, some soil insects, and fleas on pets. Have the product container or label with you when calling a poison control center or doctor, or going for treatment. Signs of toxicity. This is why you must act with great stealth and under cover of catnip. The information provided typically includes the following: Wash hands thoroughly with soap and warm water after handling. Signs of toxicity would be expected to be similar to nicotinic signs and symptoms, including lethargy, muscle fasiculations, tremors, and muscle weakness. It has been found to be highly toxic to bees and other beneficial insects. 180 Canfield St. Morgantown, WV 26505 . cats [2]. Be aware that the safety instructions for the same veterinary medicine may vary from country to country. (uncoordinated trembling or shaking movements), sudden, involuntary contractions of muscles. Although imidacloprid was listed as one of the world s be st-selling pesticides in 2000, th e European Union banned its use on outdoor crops entirely in 2018, after suspending its use in 2013 [3]. Have person sip a glass of water if able to swallow. Do not get this product in your pet’s eyes or mouth. In case of severe flea infestation, retreatment may be necessary earlier than four weeks. Reinfesting fleas are killed within 2 hours with protection against further flea infestation lasting for up to four (4) weeks. Bayer stellt Imidacloprid seit Anfang der 1990er-Jahre im industriellen Maßstab her, es wird in etwa 120 Ländern der Erde eingesetzt. 18 Oral LD 50 values in rats were estimated to be 450 mg/kg for both sexes in one study and 500 and 380 mg/kg in males and females, respectively in another study. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Every effort has been made to ensure the accuracy of the Advantage 18 (imidacloprid) Topical Solution for Cats and Kittens (8 Weeks and Older, Over 9 lbs.) ), Direction and dosage information for Advantage 18 (imidacloprid) Topical Solution for Cats and Kittens (8 Weeks and Older, Over 9 lbs. Twist cap to break seal, then remove cap from tube. For the Prevention and Treatment of Flea Infestations on Cats, ● One treatment prevents further flea infestation for up to four weeks, See Below for First Aid and Precautionary Statements. for cats (imidacloprid + moxidectin) Topical Solution Once-a-month topical solution for cats for the prevention of heartworm disease, kills adult fleas, is indicated for the treatment of flea infestations, as well as the treatment and control of ear mite infestations and intestinal parasite infections in cats and kittens 9 weeks of age and older and that weigh at least 2 lbs. It happens that some users want to save money buying large tablets or spot-ons for treating smaller dogs (or even cats!) Place the tip of the tube on the skin and squeeze the tube to expel the entire contents of the tube directly on the skin. If partly filled: Call your local solid waste agency or 1-800-422-9874 for disposal instructions. Imidacloprid was first registered in the United States (U.S.) in 1992 by Miles Inc., and was approved by the U.S. Environmental Protection Agency (EPA) in 1994 [1]. Advantage 18 Topical Solution - Purple/18 For Cats and Kittens 8 Weeks and Older and Over 9 lbs. Email: [email protected] . Health Canada has stated that the chemical's toxicity … Forest Health Technology Enterprise Team . If empty: Do not reuse or refill this container. Imidacloprid is moderately toxic if ingested. Imidacloprid is moderately soluble in water and has a moderate affinity for organic materials. It is primarily used to prevent heartworm infection. Remove one applicator tube from the package. … 11556-DEU-1 EPA Reg. Imidacloprid is toxic to birds, honey bees, mammals and earthworms. 5. The product is bitter tasting and salivation may occur for a short time if the cat licks the product immediately after treatment. Imidacloprid is moderately toxic and is linked to neurotoxic, reproductive and mutagenic effects. 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